Insomnia & Sleep Disorders.

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Insomnia & Sleep Disorders

What is it.

Insomnia encompasses difficulty falling asleep, staying asleep, or waking unrefreshed despite adequate time in bed. Sleep disorders range from insomnia and sleep apnoea to circadian rhythm disruption. All have significant downstream consequences for virtually every system in the body.

Why does it happen.

Melatonin — the hormone that governs sleep onset — is synthesised from serotonin, which is produced from tryptophan and requires B6, zinc, and magnesium as cofactors. Deficiencies in any of these delay or suppress melatonin production.

Cortisol should be lowest at night and highest in the morning. In HPA axis dysregulation, this rhythm inverts — producing elevated evening cortisol that prevents sleep onset. Blood sugar crashes during the night trigger cortisol and adrenaline release, causing waking in the 2–4am window. Thyroid imbalance disrupts circadian rhythm. Magnesium deficiency — among the most prevalent micronutrient deficiencies — produces muscle tension and neurological arousal that prevents deep sleep.

How AdeaHealth helps.

We identify the specific biological driver of your sleep disruption through targeted biomarker testing and a detailed sleep history. The protocol addresses identified deficiencies, cortisol rhythm, blood sugar regulation, and sleep environment — structured around the evidence.

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What we test and measure.

  • Cortisol: serum cortisol; HPA axis rhythm assessment
  • Magnesium: most common deficiency contributing to poor sleep architecture
  • Thyroid panel: both hypo- and hyperthyroid states disrupt sleep
  • B6, B12, folate: melatonin synthesis pathway
  • Zinc: cofactor in serotonin-to-melatonin conversion
  • Fasting glucose & HbA1c: nocturnal hypoglycaemia as a waking driver
  • Iron & ferritin: restless legs syndrome and sleep fragmentation
  • Inflammatory markers: hs-CRP; systemic inflammation disrupts sleep architecture

What you can expect.

Improved sleep latency, fewer night wakings, and better sleep quality as biological drivers are addressed. Sleep architecture — the proportion of deep and restorative sleep — typically improves within 4–8 weeks of targeted intervention.

Other conditions we address.

A Clear Path Forward

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